GENERAL HISTOLOGY

INTRODUCTION

CELL STRUCTURE

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Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]

Imagine that a protein produced in the cell that is going to exit the cell. Which of the following would be your pathway through the cell?

A	Mitochondrion ____ Chloroplast ____ Cell Membrane
B	Ribosome ____ Rough ER ____ Golgi Apparatus ____ Cell Membrane
C	Nucleus ____ Smooth ER ____ Golgi Apparatus ____ Cell Membrane
D	Nucleolus ____ Lysosome ____ Cell Membrane

Explanation:

Detailed explanation-1: -These experiments defined a pathway taken by secreted proteins, the secretory pathway: rough ER → Golgi → secretory vesicles → cell exterior.

Detailed explanation-2: -So, the correct answer is ‘Rough ER →→ Golgi apparatus →→ Cell membrane’.

Detailed explanation-3: -Proteins Leave the ER in COPII-coated Transport Vesicles These transport vesicles bud from specialized regions of the ER called ER exit sites, whose membrane lacks bound ribosomes. In most animal cells, ER exit sites seem to be randomly dispersed throughout the ER network.

Detailed explanation-4: -The Golgi processes proteins made by the endoplasmic reticulum (ER) before sending them out to the cell. Proteins enter the Golgi on the side facing the ER (cis side), and exit on the opposite side of the stack, facing the plasma membrane of the cell (trans side).

There is 1 question to complete.