GENERAL HISTOLOGY

LARGE INTESTINE

BODY OF STOMACH

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The wall of the appendix is ​​characterized by:
A
the presence of transitional epithelium in the mucous membrane
B
the presence of a large accumulation of lymphoid tissue
C
many crypts and villi
D
lack of muscle
Explanation: 

Detailed explanation-1: -The mucosa of the appendix is colonic in type. However, the most prominent feature is the abundance of lymphoid tissue that lies within both the lamina propria and submucosa (Fig. 1-15). The lymphoid tissue is particularly prominent in younger individuals, and dissipates gradually over the person’s lifetime.

Detailed explanation-2: -First, it is a concentrate of lymphoid tissue resembling Peyer’s patches and is the primary site for immunoglobulin A production which is crucial to regulate the density and quality of the intestinal flora. Second, given its shape and position, the Appendix could be a unique niche for commensal bacteria in the body.

Detailed explanation-3: -The appendix is the only known human lymphoid tissue with B cells expressing IL-6R endogenously unlike the spleen, tonsils or peripheral blood mononuclear cells (PBMC) which only express IL-6R when stimulated by a mitogen.

Detailed explanation-4: -The most characteristic property of the appendix is the presence of masses of lymphoid tissue in the mucosa and submucosa.

There is 1 question to complete.