GENERAL HISTOLOGY

Detailed explanation-1: -The urea cycle or ornithine cycle converts excess ammonia into urea in the mitochondria of liver cells. The urea forms, then enters the blood stream, is filtered by the kidneys and is ultimately excreted in the urine.

Detailed explanation-2: -The liver-the detoxification organ With the help of specific catalysts in the liver cells carbon dioxide reacts chemically with the ammonia molecule, NH3. The less toxic nitrogenous compound urea is produced together with water. This series of reactions is called the ornithine cycle.

Detailed explanation-3: -When you eat proteins, the body breaks them down into amino acids. Ammonia is produced from leftover amino acids, and it must be removed from the body. The liver produces several chemicals (enzymes) that change ammonia into a form called urea, which the body can remove in the urine.

Detailed explanation-4: -Urea is formed during nitrogen metabolism in our body. Urea formation takes place in the hepatic cells of the liver. Then the urea is released into the bloodstream. The blood reaches the kidney and filteration takes place.