GENERAL HISTOLOGY

Detailed explanation-1: -Hepatocytes, the major parenchymal cells in the liver, play pivotal roles in metabolism, detoxification, and protein synthesis. Hepatocytes also activate innate immunity against invading microorganisms by secreting innate immunity proteins.

Detailed explanation-2: -Hepatocytes are the chief functional cells of the liver and perform an astonishing number of metabolic, endocrine and secretory functions.

Detailed explanation-3: -The most common cells of the liver (making up roughly 90% of the liver’s cells) are called hepatocytes. They are all identical. These cells carry out most of the functions which the liver performs.

Detailed explanation-4: -Four major liver cell types-hepatocytes (HCs), hepatic stellate cells (HSCs), Kupffer cells (KCs), and liver sinusoidal endothelial cells (LSECs)-spatiotemporally cooperate to shape and maintain liver functions.

Detailed explanation-5: -What are Hepatocytes. Hepatocytes are specialized epithelial cells that represent nearly 80% of the total liver mass. These liver cells are polygonal in shape with well-defined borders, granular cytoplasm, and one or more large, centrally located nuclei.