GENERAL HISTOLOGY

Detailed explanation-1: -Cholecystokinin (CCK) is released from neuroendocrine cells located in the mucosa of the upper small intestine. Food molecules, primarily proteins and fats, stimulate these cells and CCK is released into the blood stream(1, 2). CCK stimulates pancreatic secretion by two possible mechanisms.

Detailed explanation-2: -Cholecystokinin stimulates the gallbladder to contract and release stored bile into the intestine. It also stimulates the secretion of pancreatic juice and may induce satiety.

Detailed explanation-3: -Regulation of Pancreatic Secretion Pancreatic juice is stimulated to flow in response to increases in the blood concentrations of two gastrointestinal hormones, secretin and cholecystokinin.

Detailed explanation-4: -Cholecystokinin (CCK) is a major gastrointestinal hormone that plays an important role in stimulation of pancreatic secretion and gall-bladder contraction, regulation of gastrointestinal motility and induction of satiety. Ingestion of fat and protein induces significant increases in plasma CCK.

Detailed explanation-5: -It plays a fundamental role in the digestive process. When fats and proteins enter your small intestine, cholecystokinin triggers your gallbladder and pancreas to contract. They deliver bile and enzymes to your duodenum to help break down the food for absorption.