GENERAL HISTOLOGY

Detailed explanation-1: -The pancreas is solid (acinar tissues), and contains drainage tubes (the pancreatic ductal system). The pancreatic juices are made in the acinar tissues, and passed by secretion into the tubes (ducts) for transport into the duodenum. The exit hole into the duodenum is called the papilla of Vater.

Detailed explanation-2: -Digestive enzymes are secreted through the apical membrane of the acinar cell into small intercalated ducts that are directly connected to increasingly larger intralobular ducts that join the main pancreatic duct.

Detailed explanation-3: -Pancreatic juice is secreted into the duodenum through duodenal papillae. Some individuals have also an accessory duct, named accessory pancreatic duct, which may be functional (that is, it also empties the contents of the exocrine pancreas into the duodenum) or non-functional.

Detailed explanation-4: -The pancreatic enzymes are drained by 2 pancreatic ducts: the duct of Wirsung (major pancreatic duct) and the duct of Santorini (minor pancreatic duct). The ventral duct forms the proximal portion of the major pancreatic duct, which opens into the duodenum via the ampulla of Vater.

Detailed explanation-5: -Bile juice is transported to the gallbladder through a duct called a hepatic duct. The bile duct and pancreatic duct open together into the duodenum and form the hepatopancreatic duct. It is guarded by a muscular valve called the sphincter of Oddi.