GENERAL HISTOLOGY

Detailed explanation-1: -Mucus covers the stomach wall with a protective layer. Hydrochloric acid helps your body break down, digest, and absorb nutrients like proteins and kills bacteria protecting the body from infections. Histamine stimulates parietal cells to secrete HCl. Hydrochloric acid kills harmful bacteria in the stomach.

Detailed explanation-2: -Gastric acid may provide an important host defense by killing ingested pathogens (5). For example, normal gastric acidity kills more than 99.9% of several gram-negative bacilli within 30 min (9), and vegetative cells of Clostridium difficile are killed within 5 to 30 min upon exposure to pH 2 to 3 buffers (17).

Detailed explanation-3: -Gastric acid secretion is stimulated primarily by histamine released from enterochromaffin-like cells in response to gastrin (17). Gastric juice consists of HCl and pepsin and can kill bacteria within 15 min when the pH is less than 3.0 (8). If the pH is raised above 4.0, bacterial overgrowth may occur.

Detailed explanation-4: -The Stomach The acidic conditions will usually kill any harmful bacteria accidentally entering via the food. The stomach also produces several enzymes including protease and lipase for the digestion of proteins and fats.

Detailed explanation-5: -Summary: Researchers have investigated the infection mechanisms used by bacteria causing severe diarrhea. Strains of Escherichia coli (commonly known as E.