GENERAL HISTOLOGY

Detailed explanation-1: -Development of diabetes mellitus in chronic pancreatitis mainly occurs due to the destruction of islet cells by pancreatic inflammation. Additionally, nutrient maldigestion leads to an impaired incretin secretion and therefore to a diminished insulin release of the remaining beta-cells[3].

Detailed explanation-2: -Diabetes occurs when glucose builds up in the blood due to the pancreas not producing enough insulin (or not using it correctly) resulting in low energy levels. Insulin is a hormone that your body’s cells need to absorb glucose. After food that you eat is digested, glucose passes into the bloodstream.

Detailed explanation-3: -In type 2 diabetes, the pancreas makes insulin, but the cells don’t respond to it as they should. This is called insulin resistance. When glucose can’t get into cells, the blood sugar level rises. Then the pancreas works harder to make even more insulin.

Detailed explanation-4: -Diabetes. Damage to insulin-producing cells in your pancreas from chronic pancreatitis can lead to diabetes, a disease that affects the way your body uses blood sugar. Pancreatic cancer. Long-standing inflammation in your pancreas caused by chronic pancreatitis is a risk factor for developing pancreatic cancer.

Detailed explanation-5: -Acute Pancreatitis. Chronic Pancreatitis. Pancreatic Cancer. Pancreatic Cysts. Pancreatic Neuroendocrine Tumors. Periampullary and Bile Duct Diseases.