GENERAL HISTOLOGY

Detailed explanation-1: -Four major liver cell types-hepatocytes (HCs), hepatic stellate cells (HSCs), Kupffer cells (KCs), and liver sinusoidal endothelial cells (LSECs)-spatiotemporally cooperate to shape and maintain liver functions. HCs constitute ∼70% of the total liver cell population.

Detailed explanation-2: -Hepatocytes. The most common cells of the liver (making up roughly 90% of the liver’s cells) are called hepatocytes. They are all identical. These cells carry out most of the functions which the liver performs.

Detailed explanation-3: -Parts That Make Up The Liver Each lobule is made up of numerous liver cells, called hepatocytes, that line up in radiating rows. Between each row are sinusoids. These small blood vessels diffuse oxygen and nutrients through their capillary walls into the liver cells.

Detailed explanation-4: -A hepatocyte is a cell of the main parenchymal tissue of the liver. Hepatocytes make up 80% of the liver’s mass.

Detailed explanation-5: -Kupffer cells are resident liver macrophages and play a critical role in maintaining liver functions. Under physiological conditions, they are the first innate immune cells and protect the liver from bacterial infections.