GENERAL HISTOLOGY

Detailed explanation-1: -The sphincter of Oddi is a cylindrically shaped smooth muscle located where the distal CBD and the main pancreatic duct meet at the entrance to the duodenum. The role of the sphincter of Oddi is to regulate the flow of bile and pancreatic enzymes into the duodenum by antegrade phasic contractions.

Detailed explanation-2: -The sphincter of Oddi is a muscular valve responsible for controlling the flow of bile and pancreatic secretions through the ampulla of Vater into the second part of the duodenum.

Detailed explanation-3: -The sphincter of Oddi (also hepatopancreatic sphincter or Glisson’s sphincter), abbreviated as SO, is a muscular valve that in some animals, including humans, controls the flow of digestive juices (bile and pancreatic juice) out of the pancreas through the ampulla of Vater into the second part of the duodenum.

Detailed explanation-4: -Anatomical and immunohistochemical investigations have demonstrated that the sphincter of Oddi is richly innervated by cholinergic, adrenergic and peptidergic neurons. In addition, neural connections exist between the sphincter, gallbladder and proximal gastrointestinal tract.

Detailed explanation-5: -The sphincter of Oddi is a muscle that opens and closes to allow bile and pancreatic juice to flow between the pancreas and the small intestine.