GENERAL HISTOLOGY

Detailed explanation-1: -Islets of Langerhans are islands of endocrine cells scattered throughout the pancreas. A number of new studies have pointed to the potential for conversion of non- islet cells in to insulin-producing -cells to replenish -cell mass as a means to treat diabetes.

Detailed explanation-2: -Pancreatic islets, also called islets of Langerhans, are groups of cells in your pancreas. The pancreas is an organ that makes hormones to help your body break down and use food. Islets contain several types of cells, including beta cells that make the hormone insulin.

Detailed explanation-3: -Organization of the Adult Pancreas In mouse islets, cells are found to be clustered together in the core of each islet, surrounded by peripheral hormone secreting cells, most abundantly cells.

Detailed explanation-4: -Insulin is a peptide hormone produced by beta cells of islets of Langerhans in the pancreas. It regulates the metabolism of carbohydrates and fats by promoting the absorption of glucose from the blood to skeletal muscles and fat tissue.

Detailed explanation-5: -When blood glucose levels rise, beta cells in the pancreas normally make the hormone insulin. Insulin triggers cells throughout the body to take up sugar from the blood.