GENERAL HISTOLOGY

Detailed explanation-1: -Excess cortisol can counteract the effects of insulin, causing insulin resistance. Acromegaly: This is a rare but serious condition that happens when you have high levels of growth hormone (GH). High levels of GH can cause increased production of glucose, which can lead to insulin resistance.

Detailed explanation-2: -Hyperinsulinemia is connected to insulin resistance-a condition in which the body doesn’t respond as it should to the effects of insulin. In that situation, the pancreas makes more insulin in order to overcome the resistance, leading to higher levels of insulin in the blood.

Detailed explanation-3: -Insulin is secreted primarily in response to glucose, while other nutrients such as free fatty acids and amino acids can augment glucose-induced insulin secretion. In addition, various hormones, such as melatonin, estrogen, leptin, growth hormone, and glucagon like peptide-1 also regulate insulin secretion.