GENERAL HISTOLOGY

Detailed explanation-1: -Scleroderma is a long-lasting disease that affects your skin, connective tissue, and internal organs. It happens when your immune system causes your body to make too much of the protein collagen, an important part of your skin. As a result, your skin gets thick and tight, and scars can form on your lungs and kidneys.

Detailed explanation-2: -The word “scleroderma” means hard skin. One of the most visible symptoms of the condition, also called systemic sclerosis, is hardening or thickening of the skin.

Detailed explanation-3: -Symptoms of scleroderma may include: Thickening and swelling of the fingers. Pale fingers that may become numb and tingle when exposed to cold or stress, known as Raynaud’s phenomenon. Joint pain. Taut, shiny, darker skin on large areas, which can cause problems with movement.