GENERAL HISTOLOGY

LYMPHATIC

LYMPHATIC SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Basophils and mast cells
A
Produce histamine and leukotrines
B
Use perforins to rupture the membranes of pathogens
C
Are the most abundant phagocytic WBS’s
D
Pick up foreign material and take it to the nearest lymph node
Explanation: 

Detailed explanation-1: -The role of human basophils and mast cells in the pathogenesis of allergic diseases has been analyzed. Purified human basophils and mast cells release several known mediators of allergic reactions, including histamine, sulfidopeptide leukotrienes, kinin-forming enzymes, and, in the case of the mast cell, PGD2.

Detailed explanation-2: -Activated basophils and mast cells release both overlapping and unique sets of inflammatory mediators, including histamine, proteoglycans, lipid mediators, proteases, chemokines, growth factors and cytokines [9].

Detailed explanation-3: -Mast cells and basophils represent the most relevant source of histamine in the immune system. Histamine is stored in cytoplasmic granules along with other amines (e.g., serotonin), proteases, proteoglycans, cytokines/chemokines, and angiogenic factors and rapidly released upon triggering with a variety of stimuli.

Detailed explanation-4: -Inflammatory molecules called leukotrienes are one of several substances which are released by mast cells during an asthma attack, and it is leukotrienes which are primarily responsible for the bronchoconstriction.

There is 1 question to complete.