GENERAL HISTOLOGY

Detailed explanation-1: -If these problems occur, too much liquid can leave the capillaries and enter the spaces between cells. If the capillaries cannot reabsorb the fluid, it will stay in the tissues, causing swelling and water retention.

Detailed explanation-2: -Edema occurs when an excessive volume of fluid accumulates in the tissues, either within cells (cellular edema) or within the collagen-mucopolysaccharide matrix distributed in the interstitial spaces (interstitial edema) [14, 42, 62, 64, 87, 88, 141, 215, 247, 279].

Detailed explanation-3: -The net pressure that drives reabsorption-the movement of fluid from the interstitial fluid back into the capillaries-is called osmotic pressure (sometimes referred to as oncotic pressure). Whereas hydrostatic pressure forces fluid out of the capillary, osmotic pressure draws fluid back in.