LYMPHATIC
LYMPHATIC SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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B cell
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T cell
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Either A or B
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None of the above
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Detailed explanation-1: -Upon stimulation by a T cell, which usually occurs in germinal centers of secondary lymphoid organs such as the spleen and lymph nodes, the activated B cell begins to differentiate into more specialized cells. Germinal center B cells may differentiate into memory B cells or plasma cells.
Detailed explanation-2: -MiR-150 regulates the differentiation of normal B cells into antibody-secreting plasma cells. Several studies have indicated that miR-150 is highly expressed in mature B cells, relatively lowly expressed in immature B cells, and has the lowest expression during the pro-B to pre-B cell transition [44, 45].
Detailed explanation-3: -Upon re-exposure to antigen, memory B cells can quickly proliferate and differentiate into plasma cells. Alternatively, they will re-enter GCs for another round of affinity maturation and CSR.