GENERAL HISTOLOGY

Detailed explanation-1: -In phase 1, antigenic stimulation through B cell antigen receptors (BCRs) induces naive B cells to differentiate into short-lived plasma cells and GC B cells in the B cell follicles. In phase 2, antigens drive GC B cells to differentiate into long-lived plasma cells and memory B cells in GCs.

Detailed explanation-2: -When stimulated by antigen, B cells undergo a series of changes in cell surface structures and in functional capabilities and differentiate into plasma cells. Plasma cells, the final stage in B cell differentiation, secrete large amounts of immunoglobulin.

Detailed explanation-3: -T cells can wipe out infected or cancerous cells. They also direct the immune response by helping B lymphocytes to eliminate invading pathogens. B cells create antibodies. B lymphocytes, also called B cells, create a type of protein called an antibody.