GENERAL HISTOLOGY

Detailed explanation-1: -The interstitial space that lies between blood vessels and cells provides the fluid and structural environment surrounding those cells. Under most conditions in most tissues, fluid from the vascular space continually filters from the microvessels into the interstitial space and is not reabsorbed (1).

Detailed explanation-2: -The interstitial compartment is composed of connective and supporting tissues within the body – called the extracellular matrix – that are situated outside the blood and lymphatic vessels and the parenchyma of organs.

Detailed explanation-3: -Interstitial space refers to the fluid-filled spaces between blood vessels, while the interstitial fluid definition is the fluid that fills interstitial space. So, interstitial fluid is a type of ECF as it is found outside the interstitial cells. It is also known as intercellular or tissue fluid.