GENERAL HISTOLOGY

Detailed explanation-1: -Helper T cells stimulate the B cell through the binding of CD40L on the T cell to CD40 on the B cell, through interaction of other TNF-TNF-receptor family ligand pairs, and by the directed release of cytokines.

Detailed explanation-2: -Although T and B cells both react with molecules that are termed “antigens, ” these lymphocytes actually respond to very different types of molecules. B cells must be able to bind intact antigens because they secrete antibodies that must recognize the pathogen directly, rather than digested remnants of the pathogen.

Detailed explanation-3: -Thymosin: The Hormone of the Thymus Thymosin stimulates the development of T cells. Throughout your childhood years, white blood cells called lymphocytes pass through the thymus, where they are transformed into T cells.

Detailed explanation-4: -Activation of B cells to proliferation and antibody secretion is dependent on soluble lymphokines secreted by activated T cells.