GENERAL HISTOLOGY

Detailed explanation-1: -Severe combined immunodeficiency (SCID) is very rare, genetic disorder, affecting between 50 and 100 children born in the U.S. every year. SCID is often called “bubble boy disease, ” made known by the 1976 movie “The Boy in the Plastic Bubble.”

Detailed explanation-2: -More formally known as severe combined immunodeficiency (SCID), the disease drew its nickname from the protective plastic bubbles that were once used to cocoon infants with the condition. One common form of SCID is caused by a mutation in the gene encoding the enzyme adenosine deaminase (ADA).

Detailed explanation-3: -Inheritance. This condition is inherited in an X-linked recessive pattern . The gene associated with this condition is located on the X chromosome, which is one of the two sex chromosomes . In males (who have only one X chromosome), one altered copy of the gene in each cell is sufficient to cause the condition.