GENERAL HISTOLOGY

Detailed explanation-1: -The spleen is located in the abdominal (tummy) area on the left side, just under the diaphragm. It is the largest of our lymphatic organs. The spleen does many things as it filters and monitors our blood. It contains a range of cells, including macrophages – the body’s garbage trucks.

Detailed explanation-2: -Blood passes through the cords and into the sinusoids where it is drained into the large trabecular veins of the spleen. Blood is filtered through gaps in the sinusoid lining, which prevents old, damaged or abnormal red blood cells from passing into the bloodstream.

Detailed explanation-3: -The spleen also removes unhealthy, old, and misshapen red blood cells from circulation. Red blood cells carry oxygen throughout the body and remove carbon dioxide (a waste product). These disc-shaped cells are filtered by the spleen based on their physical characteristics.

Detailed explanation-4: -Secondary lymphoid organs: These organs include the lymph nodes, the spleen, the tonsils and certain tissue in various mucous membrane layers in the body (for instance in the bowel).