LYMPHATIC
LYMPHATIC SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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IgM
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IgA
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IgD
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IgG
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IgE
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Detailed explanation-1: -IgM is not only the first class of antibody to appear on the surface of a developing B cell. It is also the major class secreted into the blood in the early stages of a primary antibody response, on first exposure to an antigen.
Detailed explanation-2: -All naive B cells express cell-surface IgM and IgD, yet IgM makes up less than 10% of the immunoglobulin found in plasma, where the most abundant isotype is IgG. Much of the antibody in plasma has therefore been produced by B cells that have undergone isotype switching.
Detailed explanation-3: -IgD functions as a B cell antigen receptor and may participate in B cell maturation, maintenance, activation, and silencing. Although the exact function is still unclear, IgD may be involved in humoral immune responses by regulating B cell selection and homeostasis.