LYMPHATIC
LYMPHATIC SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following antibodies is the most abundant and is passed from mother to fetus through the placenta?
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IgM
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IgA
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IgD
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IgG
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IgE
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Explanation:
Detailed explanation-1: -Placental transfer of maternal IgG antibodies to the fetus is an important mechanism that provides protection to the infant while his/her humoral response is inefficient. IgG is the only antibody class that significantly crosses the human placenta.
Detailed explanation-2: -IgG is the only antibody class that significantly crosses the human placenta. This crossing is mediated by FcRn expressed on syncytiotrophoblast cells.
Detailed explanation-3: -IgG is the only maternal immunoglobulin that can cross the placenta and provide natural passive immunity to the foetus. IgG is the most abundant class of immunoglobulins in the body constituting 75% of all of them.
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