GENERAL HISTOLOGY

LYMPHATIC

LYMPHATIC SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which of the following is a nonspecific defense cell that produces a toxin (perforin) to kill foreign cells?
A
interferons
B
cytotoxic killer T cells
C
phagocytes
D
natural killer cells
Explanation: 

Detailed explanation-1: -By recognizing the target antigen by the TCRs, T cells initiate target cell apoptosis. The main mechanism of killing the target cell by CTL is the release of cytotoxic mediators including perforin and granzyme.

Detailed explanation-2: -Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells (collectively known as cytotoxic lymphocytes) detect cells that are infected with a virus, or are transformed, and destroy them through perforin-dependent and death-receptor-dependent pathways.

There is 1 question to complete.