LYMPHATIC
LYMPHATIC SYSTEM
Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Which of the following is a nonspecific defense cell that produces a toxin (perforin) to kill foreign cells?
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interferons
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cytotoxic killer T cells
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phagocytes
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natural killer cells
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Explanation:
Detailed explanation-1: -By recognizing the target antigen by the TCRs, T cells initiate target cell apoptosis. The main mechanism of killing the target cell by CTL is the release of cytotoxic mediators including perforin and granzyme.
Detailed explanation-2: -Cytotoxic T lymphocytes (CTLs) and natural killer (NK) cells (collectively known as cytotoxic lymphocytes) detect cells that are infected with a virus, or are transformed, and destroy them through perforin-dependent and death-receptor-dependent pathways.
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