LYMPHATIC
LYMPHATIC SYSTEM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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IgM
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IgA
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IgD
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IgG
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IgE
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Detailed explanation-1: -Because IgM is the first antibody response in viral infections, this Ig class has important value for diagnosis. IgM’s pentameric structure prevents passage across the placenta.
Detailed explanation-2: -IgM is the first antibody to be produced in response to infection since it does not require ‘class switch’ to another antibody class. However, it is only synthesized as long as antigen remains present because there are no memory cells for IgM.
Detailed explanation-3: -Natural immunoglobulin M (IgM) antibodies are pentameric or hexameric macro-immunoglobulins and have been highly conserved during evolution. IgMs are initially expressed during B cell ontogeny and are the first antibodies secreted following exposure to foreign antigens.