GENERAL HISTOLOGY

LYMPHATIC

LYMPHATIC SYSTEM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which two antibody classes fix complement (to lyse cells)?
A
IgA and IgD
B
IgD and IgG
C
IgG and IgM
D
IgE and IgM
Explanation: 

Detailed explanation-1: -However, the complement fixed by IgG antibody was shown to be highly lytic both for sheep red cells and dog kidney tissue culture cells. The fixation of complement by IgM antibodies resulted in weak and relatively ineffective cytolysis of dog kidney cells, but effective haemolysis of sheep red cells.

Detailed explanation-2: -In contrast to IgG molecules that contain one Fc domain, pentameric IgM has five different Fc domains on the same molecule, facilitating rapid complement activation when a single IgM molecule recognizes a pathogen.

Detailed explanation-3: -Immunoglobulin G (IgG): This is the most common antibody. It’s in blood and other body fluids, and protects against bacterial and viral infections. IgG can take time to form after an infection or immunization.

There is 1 question to complete.