GENERAL HISTOLOGY

MUSCLE

SKELETAL MUSCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
According to the sliding filament theory, how does muscle contraction occur? (pg. 192)
A
Myosin heads form cross bridges and pull thin filaments, causing them to slide.
B
Both thick and thin filaments shorten as the muscle contracts.
C
A bands bunch up and shorten as myosin heads attach to thin filaments.
D
Myosin heads attach and detach from thin filaments, causing thin filaments to shorten.
Explanation: 

Detailed explanation-1: -The sliding filament theory explains the process of muscle contraction during which the thin filaments slide over the thick filaments, which shortens the myofibril . Each muscle fibre has an alternate light and dark band, which contains a special contractile protein, called actin and myosin respectively.

Detailed explanation-2: -According to the sliding filament theory, when a muscle cell contracts, the thin filaments slide past the thick filaments and the sarcomere shortens.-actin monomers can bind with myosin (actin has a myosin-binding site), -they are arranged in an orderly, repeating fashion.

Detailed explanation-3: -Depolarisation and calcium ion release. Actin and myosin cross-bridge formation. Sliding mechanism of actin and myosin filaments. Sarcomere shortening (muscle contraction)

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