GENERAL HISTOLOGY

MUSCLE

SKELETAL MUSCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The Ions that are responsible for moving Troponin on the Tropomyosin.
A
Sodium
B
Calcium
C
Potassium
D
Magnesium
Explanation: 

Detailed explanation-1: -Troponin, which regulates the tropomyosin, is activated by calcium, which is kept at extremely low concentrations in the sarcoplasm. If present, calcium ions bind to troponin, causing conformational changes in troponin that allow tropomyosin to move away from the myosin-binding sites on actin.

Detailed explanation-2: -Both calcium & magnesium are required for muscle contraction. Calcium binds to troponin which exposes the active sites on actin. Now myosin head can bind the active sites on actin, initiating the process of muscle contraction. The hydrolysis of ATP is used to provide energy for muscle contraction.

Detailed explanation-3: -(2) Calcium binds to troponin C, which induces a conformational change in the troponin complex. This causes tropomyosin to move deeper into the actin groove, revealing the myosin-binding sites.

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