GENERAL HISTOLOGY

MUSCLE

SKELETAL MUSCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The protein that covers the binding site on actin when a muscle is relaxed is called
A
Troponin
B
Nebulin
C
Tropomyosin
D
Myosin
Explanation: 

Detailed explanation-1: -Tropomyosin is a protein that winds around the chains of the actin filament and covers the myosin-binding sites to prevent actin from binding to myosin. Tropomyosin binds to troponin to form a troponin-tropomyosin complex.

Detailed explanation-2: -This is because myosin binding sites on the actin filaments are all covered by a rod-shaped protein called tropomyosin.

Detailed explanation-3: -Tropomyosin binds along actin filaments and regulates actin-myosin interaction in muscle and nonmuscle cells. Seven periodic amino acid repeats are proposed to correspond to actin binding sites, and the middle periods are important for cooperative activation of actin by myosin.

There is 1 question to complete.