GENERAL HISTOLOGY

MUSCLE

SKELETAL MUSCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What is a crossbridge?
A
Where myosin binds to actin
B
Where the calcium crosses into the cytoplasm
C
Where calcium binds with troponin
D
None of the answers are correct.
Explanation: 

Detailed explanation-1: -The globular heads of myosin bind actin, forming cross-bridges between the thick and thin filaments. It is important to note that the orientation of myosin molecules in the thick filaments reverses at the M line of the sarcomere.

Detailed explanation-2: -The movements of myosin appear to be a kind of molecular dance. The myosin reaches forward, binds to actin, contracts, releases actin, and then reaches forward again to bind actin in a new cycle. This process is known as myosin-actin cycling.

Detailed explanation-3: -A distinctive structure consisting of two globular heads on each myosin molecule which interact in the presence of calcium ions with specific sites on a thin actin filament. The cross-bridges contain ATPase and generate the tension developed by a muscle fibre during a muscle action.

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