GENERAL HISTOLOGY

MUSCLE

SKELETAL MUSCLE

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Which myofibril is attached to the M line?
A
Myosin
B
Actin
C
Troponin
D
Tropomyosin
Explanation: 

Detailed explanation-1: -The actin filaments are attached at their plus ends to the Z disc, which includes the crosslinking protein -actinin. The myosin filaments are anchored at the M line in the middle of the sarcomere.

Detailed explanation-2: -Titin anchors myosin filaments to the Z-disc, and two titin molecules connect to each actin filament within the Z-disc [24].

Detailed explanation-3: -The sarcomere is split into the H-zone, A-band, I-band, M line and Z line. The H-zone consists of myosin only, the I-band consists of actin only and the A-band contains both actin and myosin. The M-line holds together the thick myosin filaments. The Z-line differentiates between each sarcomere.

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