GENERAL HISTOLOGY

Detailed explanation-1: -The Purkinje cells project in turn to the deep cerebellar nuclei. They are the only output cells of the cerebellar cortex. Since the Purkinje cells are GABAergic, the output of the cerebellar cortex is wholly inhibitory.

Detailed explanation-2: -The deep cerebellar nuclei (DCN) consist of three nuclei: the fastigial (medial) nucleus, the interposed nucleus and the dentate (lateral) nucleus. Together they form the sole output of the cerebellum.

Detailed explanation-3: -The cerebellar deep nuclei are the sole outputs of the cerebellum. The fastigial nucleus is the most medially located of the cerebellar nuclei. It receives input from the vermis and from cerebellar afferents that carry vestibular, proximal somatosensory, auditory, and visual information.

Detailed explanation-4: -It receives inputs from the cerebral cortex and pontine nuclei and sends outputs to the thalamus and red nucleus. This area also regulates coordination of muscle activation and is important in visually guided movements.

Detailed explanation-5: -Two types of neuron play dominant roles in the cerebellar circuit: Purkinje cells and granule cells. Three types of axons also play dominant roles: mossy fibers and climbing fibers (which enter the cerebellum from outside), and parallel fibers (which are the axons of granule cells).