GENERAL HISTOLOGY

Detailed explanation-1: -The adrenal glands flood the body with stress hormones, such as adrenaline and cortisol.

Detailed explanation-2: -If too much cortisol floods into the brain, which is what happens with severe, sustained stress, BDNF cannot keep up the fight. Cells die. Cortisol has a fair number of dirty tricks up its sleeve when produced in large quantities, including the ability to turn off the gene that makes BDNF.

Detailed explanation-3: -High cortisol lowers oestrogen levels, which can result in the deposition of fat, often in the middle section of the body. When oestrogen is lowered from continuous stress and cortisol production, all the female hormone imbalance symptoms such as night sweats, sleep problems, and mood swings can get worse.

Detailed explanation-4: -Disorders of the adrenal glands can cause them to produce too much cortisol. The most common is a noncancerous tumor of the adrenal cortex, called an adrenal adenoma, but only a small fraction of adenomas produce too much cortisol.

Detailed explanation-5: -Testosterone activates the subcortical areas of the brain to produce aggression, while cortisol and serotonin act antagonistically with testosterone to reduce its effects.