NERVOUS SYSTEM SPECIAL SENSE
CEREBRUM
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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A hallmark of alzheimer’s Disease is:
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destruction of neurons of the nucleus basalis
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Clusters of abnormal proteins deposited outside neurons
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Abnormal bundles of protein filaments inside neurons
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Loss of neurons that inhibit acetylcholine
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Explanation:
Detailed explanation-1: -Cholinergic neurons located in the basal forebrain, including the neurons that form the nucleus basalis of Meynert, are severely lost in Alzheimer’s disease (AD). AD is the most ordinary cause of dementia affecting 25 million people worldwide.
Detailed explanation-2: -Alzheimer’s disease (AD) is conceptualized as a progressive consequence of two hallmark pathological changes in grey matter: extracellular amyloid plaques and neurofibrillary tangles.
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