GENERAL HISTOLOGY

NERVOUS SYSTEM SPECIAL SENSE

CEREBRUM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Major component of the blood brain barrier
A
endothelial tight junctions
B
epidural space
C
dural sinuses
D
blood brain barrier
Explanation: 

Detailed explanation-1: -Tight junctions. The brain endothelial tight junction (TJ) complex is a highly elaborated structure with parallel, anastomosing intramembranous protein strands, arranged as a series of multiple barriers. It is localized along the lateral membrane to completely seal the interendothelial cleft.

Detailed explanation-2: -The blood-brain barrier (BBB) is composed of specialized brain microvascular endothelial cells (BMECs) that help regulate the flow of substances into and out of the brain.

Detailed explanation-3: -1.1 Integral Membrane Proteins: Claudins, TAMPs and JAMs. 1.1. 1.2 The TAMPs: Occludin, Tricellulin and MarvelD3. 1.3 JAMs. 1.4 Scaffolding proteins of the tight junction: ZO-1, -2, -3, Cingulin and Cingulin-like protein 1 and others.

There is 1 question to complete.