GENERAL HISTOLOGY

NERVOUS SYSTEM SPECIAL SENSE

CEREBRUM

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What two psychiatric disorders have been found to be associated with basal ganglia damage?
A
Alzheimer’s and ADHD
B
ADHD and OCD
C
Huntington’s and Parkinson’s
D
ALS and OCD
Explanation: 

Detailed explanation-1: -Though motor disorders are the most common associated with the basal ganglia, recent research shows that basal ganglia disorders can lead to other dysfunctions such as obsessive–compulsive disorder (OCD) and Tourette syndrome.

Detailed explanation-2: -Basal ganglia plays a key role in the pathogenesis of OCD. This subcortical structure is composed of the caudate, lenticular nucleus (putamen and globus pallidus), nucleus accumbens, and other areas.

Detailed explanation-3: -OCD and ADHD often follow a chronic course with persistent rates of at least 40–50 %. Family studies showed high heritability in ADHD and OCD, and some genetic findings showed similar variants for both disorders of the same pathogenetic mechanisms, whereas other genetic findings may differentiate between ADHD and OCD.

There is 1 question to complete.