GENERAL HISTOLOGY

NERVOUS SYSTEM SPECIAL SENSE

SPINALCORD

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Concerning the substantia gelatinosa of Rolando, all are true EXCEPT:
A
It is concerned with exteroceptive stimuli.
B
It is found in the posterior horn of the spinal cord
C
In the upper two thoracic segments, it is called the spinal nucleus of trigeminal nerve.
D
It is found downwards even below the second lumbar segment
Explanation: 

Detailed explanation-1: -The substantia gelatinosa of Rolando (SGR) is a grey matter structure of the dorsal spinal cord primarily involved in the transmission and modulation of pain, temperature, and touch.

Detailed explanation-2: -Lamina 2, also called “substantia gelatinosa”-a term first introduced by Rolando (1824) for its translucent appearance due to its lack of myelinated fibers-consists of projection neurons (Golgi type I neurons) and local interneurons (Golgi type II neurons).

Detailed explanation-3: -The substantia gelatinosa is one point (the nucleus proprius being the other) where first order neurons of the spinothalamic tract synapse. Many and -opioid receptors, presynaptic and postsynaptic, are found on these nerve cells; they can be targeted to manage pain of distal origin.

Detailed explanation-4: -The interneurons within the Substantia gelatinosa are what synapse to the primary afferent neurons, and are where the gate mechanism occurs. Thus, the substantia gelatinosa modulates the sensory information that is coming in from the primary afferent neurons.

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