GENERAL HISTOLOGY

Detailed explanation-1: -The axons are bundled together into groups called fascicles. Each fascicle is wrapped in a layer of connective tissue called the perineurium. Finally, the entire nerve is wrapped in a layer of connective tissue called the epineurium.

Detailed explanation-2: -PERINEURIUM. Each fascicle is surrounded by a connective tissue sheath, the perineurium. The perineurium consists of concentric layers of flattened cells separated by layers of collagen (Figures 12 to 16). The number of perineurial cell layers depends on the size of the fascicle.

Detailed explanation-3: -Each nerve is covered on the outside by a dense sheath of connective tissue, the epineurium. Beneath this is a layer of fat cells, the perineurium, which forms a complete sleeve around a bundle of axons. Perineurial septae extend into the nerve and subdivide it into several bundles of fibres.

Detailed explanation-4: -A nerve fascicle is enclosed by perineurium, a layer of fascial connective tissue. Each enclosed nerve fiber in the fascicle is enclosed by a connective tissue layer of endoneurium. Bundles of nerve fascicles are called fasciculi and are constituents of a nerve trunk.