GENERAL HISTOLOGY

Detailed explanation-1: -Perineurium is a protective sheath around fasciculus . Fasciculus is a collection of neurons. Epineurium surrounds the entire nerve.

Detailed explanation-2: -Anatomy of the Peripheral Nerve Deep to the epineurium, the internal epineurium provides a loose connective tissue for the individual fascicular bundles surrounded by the perineurium.

Detailed explanation-3: -A myelin sheath is a sleeve (sheath) that’s wrapped around each nerve cell (neurons). It’s a protective layer of fat (lipids) and protein that coats the main “body” section of a neuron called the axon.

Detailed explanation-4: -Each fascicle is wrapped in a layer of connective tissue called the perineurium. Finally, the entire nerve is wrapped in a layer of connective tissue called the epineurium.

Detailed explanation-5: -A nerve is formed by a collection of nerve fascicles (bundle of nerve fibers) which are surrounded by a loose connective tissue sheath known as the epineurium. The epineurium is the outermost layer of a peripheral nerve and is the strongest of all the connective tissue layers of the nerve.