GENERAL HISTOLOGY

NERVOUS

NEUROGLIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Choose the correct statement about the ligand gated sodium channel in the synapse.
A
Pathways for all types of cations.
B
It is present in the presynaptic neuron.
C
The site of attachment for neurotransmitters.
D
Open due to voltage from the axon.
Explanation: 

Detailed explanation-1: -What happens if the correct ligand binds to ligand-gated sodium channel in a post-synaptic neuron? An excitatory post-synaptic potential occurs.

Detailed explanation-2: -How does the binding of a neurotransmitter to a receptor result in the opening of a ligand-gated ion channel? The binding of a neurotransmitter to a receptor on the postsynaptic membrane causes the associated membrane channel to change shape, allowing it to open.

Detailed explanation-3: -Ligand-gated ion channels bind neurotransmitters and open in response to ligand binding. These channels control synaptic transmission between two neurons or between a neuron and a muscle. One subfamily encompasses the Cys-loop channels, so named because of a large extracellular domain containing Cys loops.

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