GENERAL HISTOLOGY

Detailed explanation-1: -The density of sodium channels in the axolemma is highest at nodes of Ranvier, and very low along internodal membranes; sodium channels are spread more evenly within the axolemma of unmelinated axons. Fast potassium chanels are present in the paranodal regions of myelinated axons.

Detailed explanation-2: -The type of membrane channels that are found along the axolemma (axon’s membrane) are voltage-gated Na+ channels (which will depolarize the axolemma) and voltage-gated K+ channels (which will repolarize and hyperpolarize the axolemma).

Detailed explanation-3: -Voltage-gated sodium channels exist throughout the body in various cell types, while epithelial sodium channels are located primarily in the skin and kidney.

Detailed explanation-4: -The cell membrane (axolemma) of a nerve axon separates the intracellular axoplasm from the extracellular fluid.