GENERAL HISTOLOGY

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NERVOUS

NEUROGLIA

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
Susun peristiwa chemical synapse mengikut turutan.Ligand gated sodium channel terbuka. Voltage gated calcium channel terbuka.Neurotansmitter melekat pada reseptor.Neurotransmitter mengalami eksositosis.
A
1, 2, 3, 4.
B
1, 4, 3, 2.
C
2, 4, 3, 1.
D
2, 3, 4, 1.
Explanation: 

Detailed explanation-1: -When an action potential reaches the axon terminal it depolarizes the membrane and opens voltage-gated Na+ channels. Na+ ions enter the cell, further depolarizing the presynaptic membrane. This depolarization causes voltage-gated Ca2+ channels to open.

Detailed explanation-2: -Voltage-Gated Calcium Channels VGCC represent a group of channels or pores that are gated by calcium and which have permeability for the ions Ca2+. They are found in excitable cells, not only in motor neurons but also in other types of excitable cells such as non-motor neurons, glia, and muscle.

Detailed explanation-3: -Gabapentinoids, such as gabapentin and pregabalin, are selective blockers of 2 subunit-containing voltage-gated calcium channels. They are used primarily to treat epilepsy and neuropathic pain.

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