GENERAL HISTOLOGY

Detailed explanation-1: -In physiology, the all-or-none law (sometimes the all-or-none principle or all-or-nothing law) is the principle that if a single nerve fibre is stimulated, it will always give a maximal response and produce an electrical impulse of a single amplitude.

Detailed explanation-2: -An action potential occurs when the membrane depolarises to a certain threshold, if this threshold is not reached the action potential will not be triggered. This is referred to as the all-or-nothing principle in biology: it means that the power of a stimulus is not proportional to the power of the action potential.

Detailed explanation-3: -Action potentials work on an all-or-none basis. This means that an action potential is either triggered, or it isn’t – like flipping a switch. A neuron will always send the same size action potential.