GENERAL HISTOLOGY

Detailed explanation-1: -The release is also modulated by other gut peptides: vasoactive intestinal peptide (VIP), cholecystokinin (CCK), gastrin, and glucagon-like peptide-1 (GLP-1) [67]. PYY is an important mediator of the “ileal brake” that slows gastric emptying and intestinal transit in response to nutrients in the distal small intestine.

Detailed explanation-2: -It improves digestion by slowing down the emptying of food from the stomach and stimulating the production of bile in the liver as well as its release from the gall bladder. Bile acts like a detergent making the fat droplets smaller so that enzymes can break it down more easily.

Detailed explanation-3: -Blocking CCK-A receptors accelerates gastric emptying of liquid meals and abolishes the gastrocolonic reflex. Therefore, CCK may play a role as a common regulator of postprandial gallbladder contraction and pancreatic enzyme secretion as well as of gastric emptying rates under certain conditions.

Detailed explanation-4: -It plays a fundamental role in the digestive process. When fats and proteins enter your small intestine, cholecystokinin triggers your gallbladder and pancreas to contract. They deliver bile and enzymes to your duodenum to help break down the food for absorption.