GENERAL HISTOLOGY

Detailed explanation-1: -Notochord develops in the embryo as a small flexible rod made up of mesoderm cells of the embryo. Notochord runs from head to tail along with the digestive system and the nerve cord. Notochord provides skeletal support to the body of the organism. Examples of organisms having notochord: Human beings, dogs, cows, etc.

Detailed explanation-2: -The most commonly cited functions of the notochord are: as a midline tissue that provides directional signals to surrounding tissue during development, as a skeletal (structural) element, and as a vertebral precursor. In lancelets the notochord persists throughout life as the main structural support of the body.

Detailed explanation-3: -notochord, flexible rodlike structure of mesodermal cells that is the principal longitudinal structural element of chordates and of the early embryo of vertebrates, in both of which it plays an organizational role in nervous system development.

Detailed explanation-4: -Abstract. The notochord is the defining structure of the chordates, and has essential roles in vertebrate development. It serves as a source of midline signals that pattern surrounding tissues and as a major skeletal element of the developing embryo.

Detailed explanation-5: -The notochord is the main axial skeletal element of the chordate early embryo; without a fully differentiated notochord embryos fail to elongate(Odenthal et al., 1996; Saúde et al., 2000; Schulte-Merker et al., 1992; Schulte-Merker et al., 1994; Stemple et al., 1996; Talbot et al., 1995).