GENERAL HISTOLOGY

SMALL INTESTINE

BODY OF STOMACH

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
What happens to your small intestine when you have Celiac disease?
A
When eating gluten, a chemical will be produced. This chemical will break down the walls of your small intestine.
B
The Villi of the small intestine are damaged, which will prevent nutrients from properly absorbing into your body.
C
Either A or B
D
None of the above
Explanation: 

Detailed explanation-1: -Your small intestine is lined with tiny hairlike projections called villi, which absorb vitamins, minerals and other nutrients from the food you eat. Celiac disease damages the villi, leaving your body unable to absorb nutrients necessary for health and growth.

Detailed explanation-2: -When people with celiac disease eat foods with gluten, their immune system reacts by damaging the villi. Because of the damage, the villi are unable to properly absorb iron, vitamins, and other nutrients. This may cause a number of symptoms and other health problems.

Detailed explanation-3: -When people with celiac disease eat gluten (a protein found in wheat, rye, and barley), their body mounts an immune response that attacks the small intestine. These attacks lead to damage on the villi, small fingerlike projections that line the small intestine, that promote nutrient absorption.

Detailed explanation-4: -If you have coeliac disease, the mucosa (lining) of your small intestine is damaged. This causes inflammation of the villi, referred to as villous atrophy. As a result of this inflammation, the surface area of your small intestine, which enables the absorption of nutrients and minerals, is seriously reduced.

Detailed explanation-5: -When a patient with celiac disease is initially diagnosed, intestinal biopsy shows flattening of villi, the long, fingerlike projections that normally absorb nutrients and fluid. Symptoms of celiac disease, which include diarrhea, weight loss, and iron-deficiency anemia, result from damaged villi.

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