GENERAL HISTOLOGY

Detailed explanation-1: -The capillary colloid osmotic pressure (COP) is close to 24 mm Hg. Because the molecular weight of albumin is close to 70, 000 and the PAlbumin is 40 g/L, there is 0.6 mmol of albumin per liter of plasma. This would generate an osmotic pressure of close to 13 mm Hg.

Detailed explanation-2: -Colloid Osmotic Pressure COP, also referred to as oncotic pressure, results from the osmotic force created by macromolecules within the intravascular compartment and is essential to retaining appropriate intravascular volume.

Detailed explanation-3: -By far, the protein with the greatest contribution to the colloid osmotic pressure in the plasma/capillary space is albumin (21.8 mm Hg), followed by globulins (6 mm Hg), and then fibrinogen (0.2 mm Hg), giving a total colloid pressure of 28 mm Hg to move fluids inward.

Detailed explanation-4: -Albumin is the main protein maintaining oncotic pressure in the vascular compartment. Intracellular fluid status is maintained by an equilibrium of the oncotic pressure and hydrostatic pressure.