GENERAL HISTOLOGY

Detailed explanation-1: -Albuminuria is a sign of kidney disease and means that you have too much albumin in your urine. Albumin is a protein found in the blood. A healthy kidney doesn’t let albumin pass from the blood into the urine. A damaged kidney lets some albumin pass into the urine.

Detailed explanation-2: -Damage to the glomeruli from inflammation or scarring can lead to increased blood pressure. Nephrotic syndrome. Nephrotic syndrome is a condition in which there is too much blood protein in urine and too little in the bloodstream. These proteins play a role in regulating fluids and cholesterol levels.

Detailed explanation-3: -When your kidneys clean waste from your blood, tiny filters prevent the large protein molecules from leaving your body through urine. If there is a problem with your kidneys, protein can leak into your urine.

Detailed explanation-4: -Studies have shown albumin and its ligands to induce expression of inflammatory and fibrogenic mediators, and it has been hypothesized that increased filtration of albumin causes excessive tubular reabsorption, resulting in inflammation and fibrosis, resulting in the loss of renal function.