MRCP UK EXAMINATIONS

ABDOMINAL

ABDOMINAL STATION

Question [CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
The pathogen of typhoid fever has the following characteristics
A
sensitive to high temperatures
B
sensitive to low temperatures
C
sensitive to penicillin
D
None of the above
Explanation: 

Detailed explanation-1: -Pathogenesis of enteric (typhoid and paratyphoid) fever-UpToDate. Enteric fever is characterized by severe systemic illness with fever and abdominal pain [1]. The organism classically responsible for the enteric fever syndrome is Salmonella enterica serotype Typhi (formerly S. typhi).

Detailed explanation-2: -A sample of your blood, stool, urine or bone marrow is used. The sample is placed in an environment where bacteria grow easily. The growth, called a culture, is checked under a microscope for the typhoid bacteria. A bone marrow culture often is the most sensitive test for Salmonella typhi.

Detailed explanation-3: -Typhoid toxin is an unusual AB5 toxin with a unique architecture composed of a pentameric B subunit (PltB) associated with two A subunits, an ADP ribosyl transferase (PltA) and a DNase (CdtB), which are covalently linked to one another by a disulfide bond (19).

There is 1 question to complete.