ABDOMINAL
ABDOMINAL STATION
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Question
[CLICK ON ANY CHOICE TO KNOW THE RIGHT ANSWER]
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Why can the small intestine and large intestine be targets of SARS-CoV 2?
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because it has ACE-I receptors
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because it has an ACE-II receptor
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because it has goblet cells
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None of the above
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Explanation:
Detailed explanation-1: -As compared to SARS-CoV, SARS-CoV-2 appears to have a functional advantage regarding the ectodomain of the S protein and its affinity to ACE2 receptors on host cells. It is estimated that SARS-CoV-2 has an ACE2 binding affinity of approximately 15 nano Molar (nM), which is up to 20-fold higher than that of SARS-CoV.
Detailed explanation-2: -In conclusion, ACE2 is abundantly present in humans in the epithelia of the lung and small intestine, which might provide possible routes of entry for the SARS-CoV.
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